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SMILES: Cc1ccn2nc(CNc3ncnc(N)c3-c3cncc(c3)C(F)F)n(-c3ccccc3)c(=O)c12

InChI Key: InChIKey=DKIYATQFFIIBGF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 236983   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))		BDBM236983
PNG
(US9388189, 169)
Show SMILES Cc1ccn2nc(CNc3ncnc(N)c3-c3cncc(c3)C(F)F)n(-c3ccccc3)c(=O)c12
Show InChI InChI=1S/C24H20F2N8O/c1-14-7-8-33-20(14)24(35)34(17-5-3-2-4-6-17)18(32-33)12-29-23-19(22(27)30-13-31-23)15-9-16(21(25)26)11-28-10-15/h2-11,13,21H,12H2,1H3,(H3,27,29,30,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a 3n/an/an/an/an/an/a



Almirall, S.A.

US Patent


Assay Description
PI-3 Kinase HTRF kit (ref. #33-037) and the different PI3K recombinant isoforms (ref. #14-602, ref. #14-603, ref. #14-604, ref. #15-558 for Alpha, Be...

US Patent US9388189 (2016)


BindingDB Entry DOI: 10.7270/Q2K64H0P
More data for this
Ligand-Target Pair