null

SMILES: CCOc1ncc(cc1NS(=O)(=O)c1ccc(O)cc1)-c1c(N)ncnc1N[C@@H](C)c1nn2ccc(C)c2c(=O)n1-c1ccccc1

InChI Key: InChIKey=LASVPQPKADHGRS-FQEVSTJZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 236989   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM236989 (US9388189, 187) Show SMILES CCOc1ncc(cc1NS(=O)(=O)c1ccc(O)cc1)-c1c(N)ncnc1N[C@@H](C)c1nn2ccc(C)c2c(=O)n1-c1ccccc1 Show InChI InChI=1S/C32H31N9O5S/c1-4-46-31-25(39-47(44,45)24-12-10-23(42)11-13-24)16-21(17-34-31)26-28(33)35-18-36-29(26)37-20(3)30-38-40-15-14-19(2)27(40)32(43)41(30)22-8-6-5-7-9-22/h5-18,20,39,42H,4H2,1-3H3,(H3,33,35,36,37)/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Almirall, S.A. US Patent					Assay Description PI-3 Kinase HTRF kit (ref. #33-037) and the different PI3K recombinant isoforms (ref. #14-602, ref. #14-603, ref. #14-604, ref. #15-558 for Alpha, Be...				US Patent US9388189 (2016) BindingDB Entry DOI: 10.7270/Q2K64H0P
					More data for this Ligand-Target Pair