BDBM237310 2-(4-Isobutylphenyl)-N-(3-(3-methylpyridin-2-ylamino)-3-oxopropyl)propanamide (11)

SMILES: CC(C)Cc1ccc(cc1)C(C)C(=O)NCCC(=O)Nc1ncccc1C

InChI Key: InChIKey=PWCSAISFZIAKMA-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 237310   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM237310 (2-(4-Isobutylphenyl)-N-(3-(3-methylpyridin-2-ylami...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)NCCC(=O)Nc1ncccc1C Show InChI InChI=1S/C22H29N3O2/c1-15(2)14-18-7-9-19(10-8-18)17(4)22(27)24-13-11-20(26)25-21-16(3)6-5-12-23-21/h5-10,12,15,17H,11,13-14H2,1-4H3,(H,24,27)(H,23,25,26)	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	7.0	4
Umeå University					Assay Description Frozen (−80°C) brains (minus cerebella) from adult Wistar or Sprague-Dawley rats were thawed and homogenized in 20 mM HEPES, 1 mM MgCl2, pH 7....				J Enzyme Inhib Med Chem 28: 172-82 (2013) Article DOI: 10.3109/14756366.2011.643304 BindingDB Entry DOI: 10.7270/Q2BG2MWD
					More data for this Ligand-Target Pair