BDBM238314 US9394273, 3::US9394273, 4

SMILES: OC(Cc1sc2ccccc2c1Cl)\C=C\[C@H]1CCC(=O)[C@@H]1CCc1ccc(cc1)C(O)=O

InChI Key: InChIKey=XHFNHGXDNFRXKW-JKUHXCCASA-N

Data: 4 KI  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 238314   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM238314 (US9394273, 3 | US9394273, 4) Show SMILES OC(Cc1sc2ccccc2c1Cl)\C=C\[C@H]1CCC(=O)[C@@H]1CCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H25ClO4S/c27-25-21-3-1-2-4-23(21)32-24(25)15-19(28)12-10-17-11-14-22(29)20(17)13-7-16-5-8-18(9-6-16)26(30)31/h1-6,8-10,12,17,19-20,28H,7,11,13-15H2,(H,30,31)/b12-10+/t17-,19?,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	603	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf...				US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM238314 (US9394273, 3 | US9394273, 4) Show SMILES OC(Cc1sc2ccccc2c1Cl)\C=C\[C@H]1CCC(=O)[C@@H]1CCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H25ClO4S/c27-25-21-3-1-2-4-23(21)32-24(25)15-19(28)12-10-17-11-14-22(29)20(17)13-7-16-5-8-18(9-6-16)26(30)31/h1-6,8-10,12,17,19-20,28H,7,11,13-15H2,(H,30,31)/b12-10+/t17-,19?,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.31E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf...				US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM238314 (US9394273, 3 | US9394273, 4) Show SMILES OC(Cc1sc2ccccc2c1Cl)\C=C\[C@H]1CCC(=O)[C@@H]1CCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H25ClO4S/c27-25-21-3-1-2-4-23(21)32-24(25)15-19(28)12-10-17-11-14-22(29)20(17)13-7-16-5-8-18(9-6-16)26(30)31/h1-6,8-10,12,17,19-20,28H,7,11,13-15H2,(H,30,31)/b12-10+/t17-,19?,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf...				US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM238314 (US9394273, 3 | US9394273, 4) Show SMILES OC(Cc1sc2ccccc2c1Cl)\C=C\[C@H]1CCC(=O)[C@@H]1CCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H25ClO4S/c27-25-21-3-1-2-4-23(21)32-24(25)15-19(28)12-10-17-11-14-22(29)20(17)13-7-16-5-8-18(9-6-16)26(30)31/h1-6,8-10,12,17,19-20,28H,7,11,13-15H2,(H,30,31)/b12-10+/t17-,19?,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf...				US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM238314 (US9394273, 3 | US9394273, 4) Show SMILES OC(Cc1sc2ccccc2c1Cl)\C=C\[C@H]1CCC(=O)[C@@H]1CCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H25ClO4S/c27-25-21-3-1-2-4-23(21)32-24(25)15-19(28)12-10-17-11-14-22(29)20(17)13-7-16-5-8-18(9-6-16)26(30)31/h1-6,8-10,12,17,19-20,28H,7,11,13-15H2,(H,30,31)/b12-10+/t17-,19?,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.28E+3	n/a	n/a	7.4	25
ALLERGAN, INC. US Patent					Assay Description A 384-well drug plate was prepared to contain test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ce...				US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM238314 (US9394273, 3 | US9394273, 4) Show SMILES OC(Cc1sc2ccccc2c1Cl)\C=C\[C@H]1CCC(=O)[C@@H]1CCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H25ClO4S/c27-25-21-3-1-2-4-23(21)32-24(25)15-19(28)12-10-17-11-14-22(29)20(17)13-7-16-5-8-18(9-6-16)26(30)31/h1-6,8-10,12,17,19-20,28H,7,11,13-15H2,(H,30,31)/b12-10+/t17-,19?,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	186	n/a	n/a	7.4	25
ALLERGAN, INC. US Patent					Assay Description A 384-well drug plate was prepared to contain test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ce...				US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM238314 (US9394273, 3 | US9394273, 4) Show SMILES OC(Cc1sc2ccccc2c1Cl)\C=C\[C@H]1CCC(=O)[C@@H]1CCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H25ClO4S/c27-25-21-3-1-2-4-23(21)32-24(25)15-19(28)12-10-17-11-14-22(29)20(17)13-7-16-5-8-18(9-6-16)26(30)31/h1-6,8-10,12,17,19-20,28H,7,11,13-15H2,(H,30,31)/b12-10+/t17-,19?,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	7.4	25
ALLERGAN, INC. US Patent					Assay Description A 384-well drug plate was prepared to contain test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ce...				US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM238314 (US9394273, 3 | US9394273, 4) Show SMILES OC(Cc1sc2ccccc2c1Cl)\C=C\[C@H]1CCC(=O)[C@@H]1CCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H25ClO4S/c27-25-21-3-1-2-4-23(21)32-24(25)15-19(28)12-10-17-11-14-22(29)20(17)13-7-16-5-8-18(9-6-16)26(30)31/h1-6,8-10,12,17,19-20,28H,7,11,13-15H2,(H,30,31)/b12-10+/t17-,19?,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	7.4	25
ALLERGAN, INC. US Patent					Assay Description A 384-well drug plate was prepared to contain test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ce...				US Patent US9394273 (2016) BindingDB Entry DOI: 10.7270/Q2SJ1JGJ
					More data for this Ligand-Target Pair