BDBM238715 US9394297, 379
SMILES: C[C@H]1NC(=O)c2cc([nH]c12)-c1c(F)ccc2nc(C)c(NC3(C)CC3)nc12
InChI Key: InChIKey=HNGYLMVBNQDLKS-SECBINFHSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human)) | BDBM238715 (US9394297, 379) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0484 | n/a | n/a | n/a | n/a | 7.0 | 22 |
AMGEN INC. US Patent | Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)... | US Patent US9394297 (2016) BindingDB Entry DOI: 10.7270/Q2G44P78 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM238715 (US9394297, 379) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0376 | n/a | n/a | n/a | n/a | 7.0 | 22 |
AMGEN INC. US Patent | Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)... | US Patent US9394297 (2016) BindingDB Entry DOI: 10.7270/Q2G44P78 | |||||||||||
More data for this Ligand-Target Pair |