BDBM238823 US9394297, 510

SMILES: C[C@H]1NC(=O)c2cc([nH]c12)-c1c(F)ccc2c1nc(NC1(C)CC1)n(C)c2=O

InChI Key: InChIKey=OLFGXMCJTMYBMY-SECBINFHSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 238823   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238823 (US9394297, 510) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1c(F)ccc2c1nc(NC1(C)CC1)n(C)c2=O Show InChI InChI=1S/C20H20FN5O2/c1-9-15-11(17(27)22-9)8-13(23-15)14-12(21)5-4-10-16(14)24-19(26(3)18(10)28)25-20(2)6-7-20/h4-5,8-9,23H,6-7H2,1-3H3,(H,22,27)(H,24,25)/t9-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	7.0	22
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9394297 (2016) BindingDB Entry DOI: 10.7270/Q2G44P78
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238823 (US9394297, 510) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1c(F)ccc2c1nc(NC1(C)CC1)n(C)c2=O Show InChI InChI=1S/C20H20FN5O2/c1-9-15-11(17(27)22-9)8-13(23-15)14-12(21)5-4-10-16(14)24-19(26(3)18(10)28)25-20(2)6-7-20/h4-5,8-9,23H,6-7H2,1-3H3,(H,22,27)(H,24,25)/t9-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0650	n/a	n/a	n/a	n/a	7.0	22
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9394297 (2016) BindingDB Entry DOI: 10.7270/Q2G44P78
					More data for this Ligand-Target Pair