BDBM238903 US9403827, 5
SMILES: CC(C)N1C2C(N(C(=O)N=C2N=C1Br)c1cccc(Cl)c1F)c1ccc(Cl)cc1
InChI Key: InChIKey=KVODRLANFDRODC-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
p53-MDM2 (Homo sapiens (Human)) | BDBM238903![]() (US9403827, 5) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | 25 |
NOVARTIS AG US Patent | Assay Description Assay 1: This assay was used to evaluate compounds displaying inhibition of p53-MDM2 interaction and p53-MDM4 interaction at IC50s of 0.005 to 50 &mu... | US Patent US9403827 (2016) BindingDB Entry DOI: 10.7270/Q2Z31XKH | |||||||||||
More data for this Ligand-Target Pair |