BDBM239246 US9416126, D62

SMILES: CC(C)Oc1cc2c(n[nH]c2cc1F)-c1cc(ncn1)N1CCN(CCO)CC1

InChI Key: InChIKey=MYKGKVAJGAECEM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 239246   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM239246 (US9416126, D62) Show SMILES CC(C)Oc1cc2c(n[nH]c2cc1F)-c1cc(ncn1)N1CCN(CCO)CC1 Show InChI InChI=1S/C20H25FN6O2/c1-13(2)29-18-9-14-16(10-15(18)21)24-25-20(14)17-11-19(23-12-22-17)27-5-3-26(4-6-27)7-8-28/h9-13,28H,3-8H2,1-2H3,(H,24,25)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.65	n/a	n/a	n/a	n/a	8.5	25
Merck Sharp & Dohme Corp. US Patent					Assay Description a) 400 nl of a 1:2.15 serial dilution of test compound(98 μM top assay concentration) is spotted via Labcyte Echo to certain wells in a 384 well...				US Patent US9416126 (2016) BindingDB Entry DOI: 10.7270/Q2D50KV9
					More data for this Ligand-Target Pair