BDBM239657 US9394309, 113

SMILES: Cc1cc(C)c(cc1NC(=O)c1cc(Br)cc(c1)C(C)(C)C)-n1ccn2nc(cc12)-c1cccnc1

InChI Key: InChIKey=DBFQLWXYGASEET-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 239657   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor TIE-2 (Homo sapiens (Human))	BDBM239657 (US9394309, 113) Show SMILES Cc1cc(C)c(cc1NC(=O)c1cc(Br)cc(c1)C(C)(C)C)-n1ccn2nc(cc12)-c1cccnc1 Show InChI InChI=1S/C29H28BrN5O/c1-18-11-19(2)26(34-9-10-35-27(34)16-25(33-35)20-7-6-8-31-17-20)15-24(18)32-28(36)21-12-22(29(3,4)5)14-23(30)13-21/h6-17H,1-5H3,(H,32,36)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	7.0	22
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent					Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr...				US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC
					More data for this Ligand-Target Pair