BDBM240 US10201527, Compound 69::US10736881, Compound 69::US8551988, 69

SMILES: Cn1c(CNC(=O)Cc2ccc(F)cc2)nc2cc(\C=C\C(=O)NO)ccc12

InChI Key: InChIKey=PLALVIFUNPLNTF-WEVVVXLNSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 240   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM240 (US10201527, Compound 69 | US10736881, Compound 69 ...) Show SMILES Cn1c(CNC(=O)Cc2ccc(F)cc2)nc2cc(\C=C\C(=O)NO)ccc12 Show InChI InChI=1S/C20H19FN4O3/c1-25-17-8-4-13(5-9-19(26)24-28)10-16(17)23-18(25)12-22-20(27)11-14-2-6-15(21)7-3-14/h2-10,28H,11-12H2,1H3,(H,22,27)(H,24,26)/b9-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
Mei Pharma, Inc. US Patent					Assay Description The assay have been carried out in a 96 well format and the BIOMOL using a fluorescent-based HDAC activity assay.				US Patent US8551988 (2013) BindingDB Entry DOI: 10.7270/Q2BZ64P8
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM240 (US10201527, Compound 69 | US10736881, Compound 69 ...) Show SMILES Cn1c(CNC(=O)Cc2ccc(F)cc2)nc2cc(\C=C\C(=O)NO)ccc12 Show InChI InChI=1S/C20H19FN4O3/c1-25-17-8-4-13(5-9-19(26)24-28)10-16(17)23-18(25)12-22-20(27)11-14-2-6-15(21)7-3-14/h2-10,28H,11-12H2,1H3,(H,22,27)(H,24,26)/b9-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
MEI Pharma, Inc. US Patent					Assay Description The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...				US Patent US10736881 (2020)
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM240 (US10201527, Compound 69 | US10736881, Compound 69 ...) Show SMILES Cn1c(CNC(=O)Cc2ccc(F)cc2)nc2cc(\C=C\C(=O)NO)ccc12 Show InChI InChI=1S/C20H19FN4O3/c1-25-17-8-4-13(5-9-19(26)24-28)10-16(17)23-18(25)12-22-20(27)11-14-2-6-15(21)7-3-14/h2-10,28H,11-12H2,1H3,(H,22,27)(H,24,26)/b9-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
MEI PHARMA, INC. US Patent					Assay Description The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...				US Patent US10201527 (2019) BindingDB Entry DOI: 10.7270/Q2PK0J7F
					More data for this Ligand-Target Pair