BDBM24046 (2R)-2-[(4-{4-[(E)-2-(1-benzofuran-2-yl)ethenyl]phenyl}benzene)sulfonamido]-3-methylbutanoic acid::biphenylsulfonamide carboxylate, 23
SMILES: CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(\C=C\c2cc3ccccc3o2)cc1)C(O)=O
InChI Key: InChIKey=NNCMZAJUJIFSSX-OYGPHJITSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4) (Homo sapiens (Human)) | BDBM24046 ((2R)-2-[(4-{4-[(E)-2-(1-benzofuran-2-yl)ethenyl]ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Wyeth Research | Assay Description The recombinant Agg-1 proteins pretreated with the various concentrations of the compound for 10 to 15 min. The reaction was initiated by addition of... | Bioorg Med Chem Lett 16: 311-6 (2006) Article DOI: 10.1016/j.bmcl.2005.10.001 BindingDB Entry DOI: 10.7270/Q2CJ8BS1 | |||||||||||
More data for this Ligand-Target Pair |