BDBM240618 US9409882, 23

SMILES: Cc1cccc(n1)S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CC1)c1ncc(Cl)cc1F)C(=O)NC1(CC1)C#N

InChI Key: InChIKey=IRNNFVPOQXZTMG-AEFFLSMTSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 240618   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Procathepsin L (Homo sapiens (Human))	BDBM240618 (US9409882, 23) Show SMILES Cc1cccc(n1)S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CC1)c1ncc(Cl)cc1F)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C24H23ClFN5O4S/c1-14-3-2-4-19(29-14)36(34,35)16-10-18(21(32)30-23(13-27)5-6-23)31(12-16)22(33)24(7-8-24)20-17(26)9-15(25)11-28-20/h2-4,9,11,16,18H,5-8,10,12H2,1H3,(H,30,32)/t16-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.64E+3	n/a	n/a	n/a	n/a	6.5	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US9409882 (2016) BindingDB Entry DOI: 10.7270/Q2B56HNF
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM240618 (US9409882, 23) Show SMILES Cc1cccc(n1)S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CC1)c1ncc(Cl)cc1F)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C24H23ClFN5O4S/c1-14-3-2-4-19(29-14)36(34,35)16-10-18(21(32)30-23(13-27)5-6-23)31(12-16)22(33)24(7-8-24)20-17(26)9-15(25)11-28-20/h2-4,9,11,16,18H,5-8,10,12H2,1H3,(H,30,32)/t16-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	6.5	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US9409882 (2016) BindingDB Entry DOI: 10.7270/Q2B56HNF
					More data for this Ligand-Target Pair