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SMILES: COc1nc(N)nc2n(cnc12)C1OC(CO)[C@@H](O)[C@]11CCO1

InChI Key: InChIKey=RPABKOCBGNJWKU-XNWQGSSISA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 240848   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein [2420-3010]


(Hepatitis C virus genotype 1b (isolate Con1) (HCV))		BDBM240848
PNG
(US9394331, 76)
Show SMILES COc1nc(N)nc2n(cnc12)C1OC(CO)[C@@H](O)[C@]11CCO1 |r|
Show InChI InChI=1S/C13H17N5O5/c1-21-10-7-9(16-12(14)17-10)18(5-15-7)11-13(2-3-22-13)8(20)6(4-19)23-11/h5-6,8,11,19-20H,2-4H2,1H3,(H2,14,16,17)/t6?,8-,11?,13-/m1/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+5n/an/a7.527



Gilead Pharmasset LLC

US Patent


Assay Description
The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...

US Patent US9394331 (2016)


BindingDB Entry DOI: 10.7270/Q2W094TH
More data for this
Ligand-Target Pair