BDBM240926 US9409892, 21

SMILES: COc1ccc(Oc2ccc3c(O)c(nc(C#N)c3c2)C(=O)NC(C)(C)CC(O)=O)cc1

InChI Key: InChIKey=YLAYKCQTUJKINN-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 240926   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 2 (Homo sapiens (Human))	BDBM240926 (US9409892, 21) Show SMILES COc1ccc(Oc2ccc3c(O)c(nc(C#N)c3c2)C(=O)NC(C)(C)CC(O)=O)cc1 Show InChI InChI=1S/C23H21N3O6/c1-23(2,11-19(27)28)26-22(30)20-21(29)16-9-8-15(10-17(16)18(12-24)25-20)32-14-6-4-13(31-3)5-7-14/h4-10,29H,11H2,1-3H3,(H,26,30)(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	240	n/a	n/a	n/a	n/a	7.4	n/a
FibroGen, Inc. US Patent					Assay Description Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...				US Patent US9409892 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NFC
					More data for this Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase (Homo sapiens (Human))	BDBM240926 (US9409892, 21) Show SMILES COc1ccc(Oc2ccc3c(O)c(nc(C#N)c3c2)C(=O)NC(C)(C)CC(O)=O)cc1 Show InChI InChI=1S/C23H21N3O6/c1-23(2,11-19(27)28)26-22(30)20-21(29)16-9-8-15(10-17(16)18(12-24)25-20)32-14-6-4-13(31-3)5-7-14/h4-10,29H,11H2,1-3H3,(H,26,30)(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Cadila Healthcare Limited Curated by ChEMBL					Assay Description Inhibition of HIF-PHD1 (unknown origin) expressed in insect Hi5 cells using peptide as substrate				J Med Chem 61: 6964-6982 (2018) Article DOI: 10.1021/acs.jmedchem.7b01686 BindingDB Entry DOI: 10.7270/Q2H70JC7
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM240926 (US9409892, 21) Show SMILES COc1ccc(Oc2ccc3c(O)c(nc(C#N)c3c2)C(=O)NC(C)(C)CC(O)=O)cc1 Show InChI InChI=1S/C23H21N3O6/c1-23(2,11-19(27)28)26-22(30)20-21(29)16-9-8-15(10-17(16)18(12-24)25-20)32-14-6-4-13(31-3)5-7-14/h4-10,29H,11H2,1-3H3,(H,26,30)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cadila Healthcare Limited Curated by ChEMBL					Assay Description Inhibition of HIF-PHD2 (unknown origin) expressed in insect Hi5 cells using peptide as substrate				J Med Chem 61: 6964-6982 (2018) Article DOI: 10.1021/acs.jmedchem.7b01686 BindingDB Entry DOI: 10.7270/Q2H70JC7
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM240926 (US9409892, 21) Show SMILES COc1ccc(Oc2ccc3c(O)c(nc(C#N)c3c2)C(=O)NC(C)(C)CC(O)=O)cc1 Show InChI InChI=1S/C23H21N3O6/c1-23(2,11-19(27)28)26-22(30)20-21(29)16-9-8-15(10-17(16)18(12-24)25-20)32-14-6-4-13(31-3)5-7-14/h4-10,29H,11H2,1-3H3,(H,26,30)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	7.4	n/a
FibroGen, Inc. US Patent					Assay Description Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...				US Patent US9409892 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NFC
					More data for this Ligand-Target Pair