BDBM240945 US9409892, 40

SMILES: CC(C)(CNC(=O)c1nc(C#N)c2cc(Oc3ccc(Cl)cc3)ccc2c1O)C(O)=O

InChI Key: InChIKey=RNXRRHMSZOBLAT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 240945   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM240945 (US9409892, 40) Show SMILES CC(C)(CNC(=O)c1nc(C#N)c2cc(Oc3ccc(Cl)cc3)ccc2c1O)C(O)=O Show InChI InChI=1S/C22H18ClN3O5/c1-22(2,21(29)30)11-25-20(28)18-19(27)15-8-7-14(9-16(15)17(10-24)26-18)31-13-5-3-12(23)4-6-13/h3-9,27H,11H2,1-2H3,(H,25,28)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.01E+3	n/a	n/a	n/a	n/a	7.4	n/a
FibroGen, Inc. US Patent					Assay Description Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...				US Patent US9409892 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NFC
					More data for this Ligand-Target Pair
Egl nine homolog 2 (Homo sapiens (Human))	BDBM240945 (US9409892, 40) Show SMILES CC(C)(CNC(=O)c1nc(C#N)c2cc(Oc3ccc(Cl)cc3)ccc2c1O)C(O)=O Show InChI InChI=1S/C22H18ClN3O5/c1-22(2,21(29)30)11-25-20(28)18-19(27)15-8-7-14(9-16(15)17(10-24)26-18)31-13-5-3-12(23)4-6-13/h3-9,27H,11H2,1-2H3,(H,25,28)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	7.4	n/a
FibroGen, Inc. US Patent					Assay Description Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...				US Patent US9409892 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NFC
					More data for this Ligand-Target Pair