BDBM241059 US9409892, 154

SMILES: OC(=O)C1(CNC(=O)c2nc(C#N)c3cc(Sc4ccccc4)ccc3c2O)CCC1

InChI Key: InChIKey=WZEVEULDNFXEFI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 241059   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM241059 (US9409892, 154) Show SMILES OC(=O)C1(CNC(=O)c2nc(C#N)c3cc(Sc4ccccc4)ccc3c2O)CCC1 Show InChI InChI=1S/C23H19N3O4S/c24-12-18-17-11-15(31-14-5-2-1-3-6-14)7-8-16(17)20(27)19(26-18)21(28)25-13-23(22(29)30)9-4-10-23/h1-3,5-8,11,27H,4,9-10,13H2,(H,25,28)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	7.4	n/a
FibroGen, Inc. US Patent					Assay Description Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...				US Patent US9409892 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NFC
					More data for this Ligand-Target Pair
Egl nine homolog 2 (Homo sapiens (Human))	BDBM241059 (US9409892, 154) Show SMILES OC(=O)C1(CNC(=O)c2nc(C#N)c3cc(Sc4ccccc4)ccc3c2O)CCC1 Show InChI InChI=1S/C23H19N3O4S/c24-12-18-17-11-15(31-14-5-2-1-3-6-14)7-8-16(17)20(27)19(26-18)21(28)25-13-23(22(29)30)9-4-10-23/h1-3,5-8,11,27H,4,9-10,13H2,(H,25,28)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	7.4	n/a
FibroGen, Inc. US Patent					Assay Description Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...				US Patent US9409892 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NFC
					More data for this Ligand-Target Pair