null

SMILES: OCc1cc(Cl)cc(Cl)c1CNC(=O)C1COc2ncccc12

InChI Key: InChIKey=GYTSAQDZDZROII-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 241727   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM241727 (US9409917, 24 | US9409917, 25) Show SMILES OCc1cc(Cl)cc(Cl)c1CNC(=O)C1COc2ncccc12 Show InChI InChI=1S/C16H14Cl2N2O3/c17-10-4-9(7-21)12(14(18)5-10)6-20-15(22)13-8-23-16-11(13)2-1-3-19-16/h1-5,13,21H,6-8H2,(H,20,22)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description HEK cells stably expressing P2X7 were used to screen drugs using the YO-PRO1 assay. Cells were grown to confluency in adherent culture at 37° C. ...				US Patent US9409917 (2016) BindingDB Entry DOI: 10.7270/Q2ZS2VC8
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM241727 (US9409917, 24 | US9409917, 25) Show SMILES OCc1cc(Cl)cc(Cl)c1CNC(=O)C1COc2ncccc12 Show InChI InChI=1S/C16H14Cl2N2O3/c17-10-4-9(7-21)12(14(18)5-10)6-20-15(22)13-8-23-16-11(13)2-1-3-19-16/h1-5,13,21H,6-8H2,(H,20,22)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39.4	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description HEK cells stably expressing P2X7 were used to screen drugs using the YO-PRO1 assay. Cells were grown to confluency in adherent culture at 37° C. ...				US Patent US9409917 (2016) BindingDB Entry DOI: 10.7270/Q2ZS2VC8
					More data for this Ligand-Target Pair