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SMILES: O=C(NCC1(CCCCC1)c1ccccc1)C1CCOc2ncccc12

InChI Key: InChIKey=LGKRSTOHNCFTGP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 241757   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P2X purinoceptor 7


(Homo sapiens (Human))		BDBM241757
PNG
(US9409917, 54)
Show SMILES O=C(NCC1(CCCCC1)c1ccccc1)C1CCOc2ncccc12
Show InChI InChI=1S/C22H26N2O2/c25-20(18-11-15-26-21-19(18)10-7-14-23-21)24-16-22(12-5-2-6-13-22)17-8-3-1-4-9-17/h1,3-4,7-10,14,18H,2,5-6,11-13,15-16H2,(H,24,25)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 25.8n/an/an/an/an/a37



ACTELION PHARMACEUTICALS LTD.

US Patent


Assay Description
HEK cells stably expressing P2X7 were used to screen drugs using the YO-PRO1 assay. Cells were grown to confluency in adherent culture at 37° C. ...

US Patent US9409917 (2016)


BindingDB Entry DOI: 10.7270/Q2ZS2VC8
More data for this
Ligand-Target Pair