BDBM241773 US9409917, 70::US9409917, 71

SMILES: C[C@@H](NC(=O)C1COc2ncccc12)c1ccc(Cl)cc1Cl

InChI Key: InChIKey=GOCMKLPZAAFVSY-CGCSKFHYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 241773   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM241773 (US9409917, 70 | US9409917, 71) Show SMILES C[C@@H](NC(=O)C1COc2ncccc12)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C16H14Cl2N2O2/c1-9(11-5-4-10(17)7-14(11)18)20-15(21)13-8-22-16-12(13)3-2-6-19-16/h2-7,9,13H,8H2,1H3,(H,20,21)/t9-,13?/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36.5	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description HEK cells stably expressing P2X7 were used to screen drugs using the YO-PRO1 assay. Cells were grown to confluency in adherent culture at 37° C. ...				US Patent US9409917 (2016) BindingDB Entry DOI: 10.7270/Q2ZS2VC8
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM241773 (US9409917, 70 | US9409917, 71) Show SMILES C[C@@H](NC(=O)C1COc2ncccc12)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C16H14Cl2N2O2/c1-9(11-5-4-10(17)7-14(11)18)20-15(21)13-8-22-16-12(13)3-2-6-19-16/h2-7,9,13H,8H2,1H3,(H,20,21)/t9-,13?/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description HEK cells stably expressing P2X7 were used to screen drugs using the YO-PRO1 assay. Cells were grown to confluency in adherent culture at 37° C. ...				US Patent US9409917 (2016) BindingDB Entry DOI: 10.7270/Q2ZS2VC8
					More data for this Ligand-Target Pair