BDBM241782 US9409917, 79::US9409917, 80

SMILES: Clc1cc(Cl)c(CNC(=O)C2COc3ncccc23)c(Br)c1

InChI Key: InChIKey=CPNMRHDPBLHWCX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 241782   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM241782 (US9409917, 79 | US9409917, 80) Show SMILES Clc1cc(Cl)c(CNC(=O)C2COc3ncccc23)c(Br)c1 Show InChI InChI=1S/C15H11BrCl2N2O2/c16-12-4-8(17)5-13(18)10(12)6-20-14(21)11-7-22-15-9(11)2-1-3-19-15/h1-5,11H,6-7H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description HEK cells stably expressing P2X7 were used to screen drugs using the YO-PRO1 assay. Cells were grown to confluency in adherent culture at 37° C. ...				US Patent US9409917 (2016) BindingDB Entry DOI: 10.7270/Q2ZS2VC8
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM241782 (US9409917, 79 | US9409917, 80) Show SMILES Clc1cc(Cl)c(CNC(=O)C2COc3ncccc23)c(Br)c1 Show InChI InChI=1S/C15H11BrCl2N2O2/c16-12-4-8(17)5-13(18)10(12)6-20-14(21)11-7-22-15-9(11)2-1-3-19-15/h1-5,11H,6-7H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	51.1	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description HEK cells stably expressing P2X7 were used to screen drugs using the YO-PRO1 assay. Cells were grown to confluency in adherent culture at 37° C. ...				US Patent US9409917 (2016) BindingDB Entry DOI: 10.7270/Q2ZS2VC8
					More data for this Ligand-Target Pair