BDBM241796 US9409917, 93

SMILES: OCCOCc1cc(Cl)cc(Cl)c1CNC(=O)C1COc2ncccc12

InChI Key: InChIKey=XOMZGLXVHMQEEG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 241796   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM241796 (US9409917, 93) Show SMILES OCCOCc1cc(Cl)cc(Cl)c1CNC(=O)C1COc2ncccc12 Show InChI InChI=1S/C18H18Cl2N2O4/c19-12-6-11(9-25-5-4-23)14(16(20)7-12)8-22-17(24)15-10-26-18-13(15)2-1-3-21-18/h1-3,6-7,15,23H,4-5,8-10H2,(H,22,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.4	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description HEK cells stably expressing P2X7 were used to screen drugs using the YO-PRO1 assay. Cells were grown to confluency in adherent culture at 37° C. ...				US Patent US9409917 (2016) BindingDB Entry DOI: 10.7270/Q2ZS2VC8
					More data for this Ligand-Target Pair