null
SMILES: CCC(CC)(c1ccc(CCC(=O)NO)c(C)c1)c1ccc(OC[C@H](O)C(C)(C)C)c(C)c1
InChI Key: InChIKey=RWZNNVOXLNXTEQ-VWLOTQADSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone deacetylase 6 (Homo sapiens (Human)) | BDBM242902 (US9428447, JFD-50) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.61E+4 | n/a | n/a | n/a | n/a | 8.1 | 37 |
The Royal Institution for the Advancement of Learning/McGill University US Patent | Assay Description Boc-Lys(Ac)-7-amino-4-methylcoumarin (Boc-Lys(Ac)-AMC) was used as substrate for the HDAC assays. Substrate solution was prepared as follow: Boc(Lys-... | US Patent US9428447 (2016) BindingDB Entry DOI: 10.7270/Q2TX3D9H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 3 (Homo sapiens (Human)) | BDBM242902 (US9428447, JFD-50) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.51E+4 | n/a | n/a | n/a | n/a | 8.1 | 37 |
The Royal Institution for the Advancement of Learning/McGill University US Patent | Assay Description Boc-Lys(Ac)-7-amino-4-methylcoumarin (Boc-Lys(Ac)-AMC) was used as substrate for the HDAC assays. Substrate solution was prepared as follow: Boc(Lys-... | US Patent US9428447 (2016) BindingDB Entry DOI: 10.7270/Q2TX3D9H | |||||||||||
More data for this Ligand-Target Pair |