BDBM244147 US9428492, 17

SMILES: C[C@H](O)c1nc(C)nn1-c1cc(nc(n1)C(F)(F)F)C1C[C@H]1c1nc2ccccc2n1C

InChI Key: InChIKey=PIPXXCIAJLPPBJ-RDWQBYKPSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 244147   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 10A (PDE10A2) (Homo sapiens (Human))	BDBM244147 (US9428492, 17) Show SMILES C[C@H](O)c1nc(C)nn1-c1cc(nc(n1)C(F)(F)F)C1C[C@H]1c1nc2ccccc2n1C |r| Show InChI InChI=1S/C21H20F3N7O/c1-10(32)18-25-11(2)29-31(18)17-9-15(27-20(28-17)21(22,23)24)12-8-13(12)19-26-14-6-4-5-7-16(14)30(19)3/h4-7,9-10,12-13,32H,8H2,1-3H3/t10-,12?,13+/m0/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.80	-11.7	n/a	n/a	n/a	n/a	n/a	7.2	25
Merck Sharp & Dohme Corp. US Patent					Assay Description The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...				US Patent US9428492 (2016) BindingDB Entry DOI: 10.7270/Q2HD7TKM
					More data for this Ligand-Target Pair