BDBM24871 2-acetamido-N-[1-({4-[2-(methylsulfanyl)-6-phenylpyrido[2,3-d]pyrimidin-7-yl]phenyl}methyl)piperidin-4-yl]acetamide::Pyridopyrimidine, 13d

SMILES: CSc1ncc2cc(-c3ccccc3)c(nc2n1)-c1ccc(CN2CCC(CC2)NC(=O)CNC(C)=O)cc1

InChI Key: InChIKey=QCSBUEMDGVYHPM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24871   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase AKT2 (Homo sapiens (Human))	BDBM24871 (2-acetamido-N-[1-({4-[2-(methylsulfanyl)-6-phenylp...) Show SMILES CSc1ncc2cc(-c3ccccc3)c(nc2n1)-c1ccc(CN2CCC(CC2)NC(=O)CNC(C)=O)cc1 Show InChI InChI=1S/C30H32N6O2S/c1-20(37)31-18-27(38)33-25-12-14-36(15-13-25)19-21-8-10-23(11-9-21)28-26(22-6-4-3-5-7-22)16-24-17-32-30(39-2)35-29(24)34-28/h3-11,16-17,25H,12-15,18-19H2,1-2H3,(H,31,37)(H,33,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description Purified recombinant human Akt kinase was monitored for kinase activity in the presence or absence of inhibitors in a 96-well format. Detection was d...				Bioorg Med Chem Lett 18: 1274-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.054 BindingDB Entry DOI: 10.7270/Q2G73C02
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM24871 (2-acetamido-N-[1-({4-[2-(methylsulfanyl)-6-phenylp...) Show SMILES CSc1ncc2cc(-c3ccccc3)c(nc2n1)-c1ccc(CN2CCC(CC2)NC(=O)CNC(C)=O)cc1 Show InChI InChI=1S/C30H32N6O2S/c1-20(37)31-18-27(38)33-25-12-14-36(15-13-25)19-21-8-10-23(11-9-21)28-26(22-6-4-3-5-7-22)16-24-17-32-30(39-2)35-29(24)34-28/h3-11,16-17,25H,12-15,18-19H2,1-2H3,(H,31,37)(H,33,38)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	286	n/a	n/a	n/a	n/a	7.5	22
Merck Research Laboratories					Assay Description Purified recombinant human Akt kinase was monitored for kinase activity in the presence or absence of inhibitors in a 96-well format. Detection was d...				Bioorg Med Chem Lett 18: 1274-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.054 BindingDB Entry DOI: 10.7270/Q2G73C02
					More data for this Ligand-Target Pair