BDBM24964 organophosphorus derivative, 5::{[(2S)-2-amino-3-phenylpropanamido]methyl}(methyl)phosphinic acid

SMILES: CP(O)(=O)CNC(=O)[C@@H](N)Cc1ccccc1

InChI Key: InChIKey=VSYRLEOKFZDZRX-JTQLQIEISA-N

Data: 2 KI  2 IC50

PDB links: 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24964   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urea Amidohydrolase (Proteus vulgaris)	BDBM24964 (organophosphorus derivative, 5 | {[(2S)-2-amino-3-...) Show SMILES CP(O)(=O)CNC(=O)[C@@H](N)Cc1ccccc1 |r| Show InChI InChI=1S/C11H17N2O3P/c1-17(15,16)8-13-11(14)10(12)7-9-5-3-2-4-6-9/h2-6,10H,7-8,12H2,1H3,(H,13,14)(H,15,16)/t10-/m0/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.76E+5	-5.20	7.54E+5	n/a	n/a	n/a	n/a	7.0	30
Wroclaw University of Technology					Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati...				J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91
					More data for this Ligand-Target Pair
Urea Amidohydrolase (Bacillus pasteurii)	BDBM24964 (organophosphorus derivative, 5 | {[(2S)-2-amino-3-...) Show SMILES CP(O)(=O)CNC(=O)[C@@H](N)Cc1ccccc1 |r| Show InChI InChI=1S/C11H17N2O3P/c1-17(15,16)8-13-11(14)10(12)7-9-5-3-2-4-6-9/h2-6,10H,7-8,12H2,1H3,(H,13,14)(H,15,16)/t10-/m0/s1	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.15E+5	-5.08	6.00E+5	n/a	n/a	n/a	n/a	7.0	30
Wroclaw University of Technology					Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati...				J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91
					More data for this Ligand-Target Pair