null

SMILES: CCc1nn(C)c(CC)c1S(=O)(=O)N1CCC(CC1)Oc1ccc(Cl)cc1Cl

InChI Key: InChIKey=YJHPFQHKOBNEJT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 250549   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM250549 (US10167273, Example 28 | US10544126, Example 28 | ...) Show SMILES CCc1nn(C)c(CC)c1S(=O)(=O)N1CCC(CC1)Oc1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H25Cl2N3O3S/c1-4-16-19(17(5-2)23(3)22-16)28(25,26)24-10-8-14(9-11-24)27-18-7-6-13(20)12-15(18)21/h6-7,12,14H,4-5,8-11H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	320	n/a	n/a	n/a	n/a	7.4	37
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9475795 (2016) BindingDB Entry DOI: 10.7270/Q20Z727W
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM250549 (US10167273, Example 28 | US10544126, Example 28 | ...) Show SMILES CCc1nn(C)c(CC)c1S(=O)(=O)N1CCC(CC1)Oc1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H25Cl2N3O3S/c1-4-16-19(17(5-2)23(3)22-16)28(25,26)24-10-8-14(9-11-24)27-18-7-6-13(20)12-15(18)21/h6-7,12,14H,4-5,8-11H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2CV4NKN
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM250549 (US10167273, Example 28 | US10544126, Example 28 | ...) Show SMILES CCc1nn(C)c(CC)c1S(=O)(=O)N1CCC(CC1)Oc1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H25Cl2N3O3S/c1-4-16-19(17(5-2)23(3)22-16)28(25,26)24-10-8-14(9-11-24)27-18-7-6-13(20)12-15(18)21/h6-7,12,14H,4-5,8-11H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US10544126 (2020) BindingDB Entry DOI: 10.7270/Q2MP55NK
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM250549 (US10167273, Example 28 | US10544126, Example 28 | ...) Show SMILES CCc1nn(C)c(CC)c1S(=O)(=O)N1CCC(CC1)Oc1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H25Cl2N3O3S/c1-4-16-19(17(5-2)23(3)22-16)28(25,26)24-10-8-14(9-11-24)27-18-7-6-13(20)12-15(18)21/h6-7,12,14H,4-5,8-11H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US10167273 (2019) BindingDB Entry DOI: 10.7270/Q24F1ST0
					More data for this Ligand-Target Pair