Found 5 hits for monomerid = 250755 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM250755
![PNG](/data/jpeg/tenK25/BindingDB_250755.png) (US9452986, 59)Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)NC2CC(F)(F)C2)nc1 Show InChI InChI=1S/C20H14F5N3O2/c21-19(22)8-13(9-19)27-18(29)16-4-1-11-7-14(3-5-15(11)28-16)30-17-6-2-12(10-26-17)20(23,24)25/h1-7,10,13H,8-9H2,(H,27,29) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
AbbVie Inc.
US Patent
| Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ... |
US Patent US9452986 (2016)
BindingDB Entry DOI: 10.7270/Q2MS3RQS |
More data for this Ligand-Target Pair | |
Sodium channel protein type 10 subunit alpha
(Homo sapiens (Human)) | BDBM250755
![PNG](/data/jpeg/tenK25/BindingDB_250755.png) (US9452986, 59)Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)NC2CC(F)(F)C2)nc1 Show InChI InChI=1S/C20H14F5N3O2/c21-19(22)8-13(9-19)27-18(29)16-4-1-11-7-14(3-5-15(11)28-16)30-17-6-2-12(10-26-17)20(23,24)25/h1-7,10,13H,8-9H2,(H,27,29) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 1.53E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
AbbVie Inc.
US Patent
| Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl... |
US Patent US9452986 (2016)
BindingDB Entry DOI: 10.7270/Q2MS3RQS |
More data for this Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM250755
![PNG](/data/jpeg/tenK25/BindingDB_250755.png) (US9452986, 59)Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)NC2CC(F)(F)C2)nc1 Show InChI InChI=1S/C20H14F5N3O2/c21-19(22)8-13(9-19)27-18(29)16-4-1-11-7-14(3-5-15(11)28-16)30-17-6-2-12(10-26-17)20(23,24)25/h1-7,10,13H,8-9H2,(H,27,29) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116743 BindingDB Entry DOI: 10.7270/Q2BP06V9 |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM250755
![PNG](/data/jpeg/tenK25/BindingDB_250755.png) (US9452986, 59)Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)NC2CC(F)(F)C2)nc1 Show InChI InChI=1S/C20H14F5N3O2/c21-19(22)8-13(9-19)27-18(29)16-4-1-11-7-14(3-5-15(11)28-16)30-17-6-2-12(10-26-17)20(23,24)25/h1-7,10,13H,8-9H2,(H,27,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116743 BindingDB Entry DOI: 10.7270/Q2BP06V9 |
More data for this Ligand-Target Pair | |
Sodium channel protein type 7 subunit alpha
(Homo sapiens (Human)) | BDBM250755
![PNG](/data/jpeg/tenK25/BindingDB_250755.png) (US9452986, 59)Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)NC2CC(F)(F)C2)nc1 Show InChI InChI=1S/C20H14F5N3O2/c21-19(22)8-13(9-19)27-18(29)16-4-1-11-7-14(3-5-15(11)28-16)30-17-6-2-12(10-26-17)20(23,24)25/h1-7,10,13H,8-9H2,(H,27,29) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116743 BindingDB Entry DOI: 10.7270/Q2BP06V9 |
More data for this Ligand-Target Pair | |