null
SMILES: CN1CCN(CC1)C(=O)c1ccc2cc(Oc3ccccn3)ccc2n1
InChI Key: InChIKey=WTYDLIVNXOKESA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 250773 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM250773
(US9452986, 77)Show InChI InChI=1S/C20H20N4O2/c1-23-10-12-24(13-11-23)20(25)18-7-5-15-14-16(6-8-17(15)22-18)26-19-4-2-3-9-21-19/h2-9,14H,10-13H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | 37 |
AbbVie Inc.
US Patent
| Assay Description
Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ... |
US Patent US9452986 (2016)
BindingDB Entry DOI: 10.7270/Q2MS3RQS |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM250773
(US9452986, 77)Show InChI InChI=1S/C20H20N4O2/c1-23-10-12-24(13-11-23)20(25)18-7-5-15-14-16(6-8-17(15)22-18)26-19-4-2-3-9-21-19/h2-9,14H,10-13H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.68E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116743
BindingDB Entry DOI: 10.7270/Q2BP06V9 |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 7 subunit alpha
(Homo sapiens (Human)) | BDBM250773
(US9452986, 77)Show InChI InChI=1S/C20H20N4O2/c1-23-10-12-24(13-11-23)20(25)18-7-5-15-14-16(6-8-17(15)22-18)26-19-4-2-3-9-21-19/h2-9,14H,10-13H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116743
BindingDB Entry DOI: 10.7270/Q2BP06V9 |
More data for this
Ligand-Target Pair | |
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