BDBM250786 US9452986, 90

SMILES: O=C(N[C@H]1CCOC1=O)c1ccc2cc(Oc3ccc(cc3)C#N)ccc2n1

InChI Key: InChIKey=OIHLAZOYTBWLPU-IBGZPJMESA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 250786   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250786 (US9452986, 90) Show SMILES O=C(N[C@H]1CCOC1=O)c1ccc2cc(Oc3ccc(cc3)C#N)ccc2n1 Show InChI InChI=1S/C21H15N3O4/c22-12-13-1-4-15(5-2-13)28-16-6-8-17-14(11-16)3-7-18(23-17)20(25)24-19-9-10-27-21(19)26/h1-8,11,19H,9-10H2,(H,24,25)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	368	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair