BDBM250870 US9452986, 174

SMILES: FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)NCCN2CCCC2)nc1

InChI Key: InChIKey=RDEALRLGUVUSJX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 250870   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250870 (US9452986, 174) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)NCCN2CCCC2)nc1 Show InChI InChI=1S/C22H21F3N4O2/c23-22(24,25)16-4-8-20(27-14-16)31-17-5-7-18-15(13-17)3-6-19(28-18)21(30)26-9-12-29-10-1-2-11-29/h3-8,13-14H,1-2,9-12H2,(H,26,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	294	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair