BDBM250926 US9452986, 230

SMILES: FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)N[C@@H]2CC[C@H]3CN(Cc4ccccc4)C[C@@H]23)nc1

InChI Key: InChIKey=GAKMQJJNGCNNNN-BBVWWWHTSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 250926   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250926 (US9452986, 230) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)N[C@@H]2CC[C@H]3CN(Cc4ccccc4)C[C@@H]23)nc1 Show InChI InChI=1S/C30H27F3N4O2/c31-30(32,33)22-8-13-28(34-15-22)39-23-9-12-25-20(14-23)6-11-27(35-25)29(38)36-26-10-7-21-17-37(18-24(21)26)16-19-4-2-1-3-5-19/h1-6,8-9,11-15,21,24,26H,7,10,16-18H2,(H,36,38)/t21-,24+,26+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	259	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
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