Found 4 hits for monomerid = 250947 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM250947
(US9452986, 251)Show SMILES CS(=O)(=O)CCNC(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C19H16F3N3O4S/c1-30(27,28)9-8-23-18(26)16-5-2-12-10-14(4-6-15(12)25-16)29-17-7-3-13(11-24-17)19(20,21)22/h2-7,10-11H,8-9H2,1H3,(H,23,26) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.59E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
AbbVie Inc.
US Patent
| Assay Description
Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ... |
US Patent US9452986 (2016)
BindingDB Entry DOI: 10.7270/Q2MS3RQS |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM250947
(US9452986, 251)Show SMILES CS(=O)(=O)CCNC(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C19H16F3N3O4S/c1-30(27,28)9-8-23-18(26)16-5-2-12-10-14(4-6-15(12)25-16)29-17-7-3-13(11-24-17)19(20,21)22/h2-7,10-11H,8-9H2,1H3,(H,23,26) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116743
BindingDB Entry DOI: 10.7270/Q2BP06V9 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM250947
(US9452986, 251)Show SMILES CS(=O)(=O)CCNC(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C19H16F3N3O4S/c1-30(27,28)9-8-23-18(26)16-5-2-12-10-14(4-6-15(12)25-16)29-17-7-3-13(11-24-17)19(20,21)22/h2-7,10-11H,8-9H2,1H3,(H,23,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116743
BindingDB Entry DOI: 10.7270/Q2BP06V9 |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 7 subunit alpha
(Homo sapiens (Human)) | BDBM250947
(US9452986, 251)Show SMILES CS(=O)(=O)CCNC(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C19H16F3N3O4S/c1-30(27,28)9-8-23-18(26)16-5-2-12-10-14(4-6-15(12)25-16)29-17-7-3-13(11-24-17)19(20,21)22/h2-7,10-11H,8-9H2,1H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.48E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116743
BindingDB Entry DOI: 10.7270/Q2BP06V9 |
More data for this
Ligand-Target Pair | |
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