BDBM251010 US9452986, 314

SMILES: FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)N2CCC(C2)N2CCC2)nc1

InChI Key: InChIKey=DYCBLARGWSKQBV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 251010   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251010 (US9452986, 314) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)N2CCC(C2)N2CCC2)nc1 Show InChI InChI=1S/C23H21F3N4O2/c24-23(25,26)16-3-7-21(27-13-16)32-18-4-6-19-15(12-18)2-5-20(28-19)22(31)30-11-8-17(14-30)29-9-1-10-29/h2-7,12-13,17H,1,8-11,14H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	218	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair