BDBM251142 US9452986, 446

SMILES: CCN(CC)C(=O)CNC(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1

InChI Key: InChIKey=GSMIBYSHBGOSKC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 251142   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251142 (US9452986, 446) Show SMILES CCN(CC)C(=O)CNC(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C22H21F3N4O3/c1-3-29(4-2)20(30)13-27-21(31)18-8-5-14-11-16(7-9-17(14)28-18)32-19-10-6-15(12-26-19)22(23,24)25/h5-12H,3-4,13H2,1-2H3,(H,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	166	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair