BDBM251149 US9452986, 453

SMILES: CCN(CC)C(=O)CCNC(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1

InChI Key: InChIKey=BDPSUZAMBCEYNR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 251149   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251149 (US9452986, 453) Show SMILES CCN(CC)C(=O)CCNC(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C23H23F3N4O3/c1-3-30(4-2)21(31)11-12-27-22(32)19-8-5-15-13-17(7-9-18(15)29-19)33-20-10-6-16(14-28-20)23(24,25)26/h5-10,13-14H,3-4,11-12H2,1-2H3,(H,27,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	405	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair