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BDBM252625 US9458176, 22

SMILES: Cc1cc(cc(C)n1)-c1nc(-c2ccc(OC3CC3)c(C)c2)n2C[C@@H](CF)OCCc12

InChI Key: InChIKey=JEKQTOPNJIBCNC-OAQYLSRUSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 252625   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))		BDBM252625
PNG
(US9458176, 22)
Show SMILES Cc1cc(cc(C)n1)-c1nc(-c2ccc(OC3CC3)c(C)c2)n2C[C@@H](CF)OCCc12 |r|
Show InChI InChI=1S/C25H28FN3O2/c1-15-10-18(4-7-23(15)31-20-5-6-20)25-28-24(19-11-16(2)27-17(3)12-19)22-8-9-30-21(13-26)14-29(22)25/h4,7,10-12,20-21H,5-6,8-9,13-14H2,1-3H3/t21-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.10n/an/an/an/an/a25



Eisai R&D Management Co., Ltd.

US Patent


Assay Description
The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...

US Patent US9458176 (2016)


BindingDB Entry DOI: 10.7270/Q2PK0F3D
More data for this
Ligand-Target Pair