BDBM252628 US9458176, 25
SMILES: COc1cc(ccc1OC(F)(F)F)-c1nc(c2CCO[C@H](C)Cn12)-c1cc(C)nc(C)c1
InChI Key: InChIKey=MWDRSYUFMFFQEH-OAHLLOKOSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM252628 (US9458176, 25) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | 25 |
Eisai R&D Management Co., Ltd. US Patent | Assay Description The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ... | US Patent US9458176 (2016) BindingDB Entry DOI: 10.7270/Q2PK0F3D | |||||||||||
More data for this Ligand-Target Pair |