BindingDB logo
myBDB logout

null

SMILES: C[C@@H]1Cn2c(CCO1)c(nc2-c1ccc(OC2CC2)c(Cl)c1)-c1ccnc(C)c1

InChI Key: InChIKey=UPJQLLBDSATFCN-OAHLLOKOSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 252762   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))		BDBM252762
PNG
(US9458176, 159)
Show SMILES C[C@@H]1Cn2c(CCO1)c(nc2-c1ccc(OC2CC2)c(Cl)c1)-c1ccnc(C)c1 |r|
Show InChI InChI=1S/C23H24ClN3O2/c1-14-11-16(7-9-25-14)22-20-8-10-28-15(2)13-27(20)23(26-22)17-3-6-21(19(24)12-17)29-18-4-5-18/h3,6-7,9,11-12,15,18H,4-5,8,10,13H2,1-2H3/t15-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/a25



Eisai R&D Management Co., Ltd.

US Patent


Assay Description
The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...

US Patent US9458176 (2016)


BindingDB Entry DOI: 10.7270/Q2PK0F3D
More data for this
Ligand-Target Pair