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SMILES: COc1ccc(NC(=O)C2=C(C[C@](NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccn(n2)C2CC2)cc1

InChI Key: InChIKey=MOVYPDIMXRKCLI-NDEPHWFRSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 253652   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))		BDBM253652
PNG
(US9701672, 76)
Show SMILES COc1ccc(NC(=O)C2=C(C[C@](NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccn(n2)C2CC2)cc1 |r,t:9|
Show InChI InChI=1S/C30H28F6N4O4/c1-43-21-11-5-19(6-12-21)37-26(41)25-23(24-13-15-40(39-24)20-7-8-20)17-28(30(34,35)36,38-27(25)42)18-3-9-22(10-4-18)44-16-2-14-29(31,32)33/h3-6,9-13,15,20H,2,7-8,14,16-17H2,1H3,(H,37,41)(H,38,42)/t28-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.20n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...

US Patent US9701672 (2017)


BindingDB Entry DOI: 10.7270/Q2DV1MXW
More data for this
Ligand-Target Pair