BDBM253882 US9459250, E87

SMILES: Fc1ccc(cc1Cl)C(=O)Nc1nnc(s1)C(F)(F)F

InChI Key: InChIKey=RURYTEMNIFIKOT-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 253882   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
T1R2/T1R3 (Homo sapiens (Human))	BDBM253882 (US9459250, E87) Show SMILES Fc1ccc(cc1Cl)C(=O)Nc1nnc(s1)C(F)(F)F Show InChI InChI=1S/C10H4ClF4N3OS/c11-5-3-4(1-2-6(5)12)7(19)16-9-18-17-8(20-9)10(13,14)15/h1-3H,(H,16,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.55E+3	n/a	n/a	n/a	10
SENOMYX, INC. US Patent					Assay Description Immunoassays also often use a labeling agent to specifically bind to and label the complex formed by the antibody and antigen. The labeling agent may...				US Patent US9459250 (2016) BindingDB Entry DOI: 10.7270/Q2D21WJB
					More data for this Ligand-Target Pair