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SMILES: COc1ccc(cc1C1=C(CN2[C@@H](C)[C@H](OC2=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)CC(C)(C)CC1)-c1ccc(cc1OC)C(O)=O

InChI Key: InChIKey=ULFFPOHPUXJZFI-RQZFFVEVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254042   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))		BDBM254042
PNG
(US9493430, 597)
Show SMILES COc1ccc(cc1C1=C(CN2[C@@H](C)[C@H](OC2=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)CC(C)(C)CC1)-c1ccc(cc1OC)C(O)=O |r,c:9|
Show InChI InChI=1S/C36H35F6NO6/c1-19-31(22-12-24(35(37,38)39)16-25(13-22)36(40,41)42)49-33(46)43(19)18-23-17-34(2,3)11-10-26(23)28-14-20(7-9-29(28)47-4)27-8-6-21(32(44)45)15-30(27)48-5/h6-9,12-16,19,31H,10-11,17-18H2,1-5H3,(H,44,45)/t19-,31-/m0/s1
PDB
MMDB

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PC cid
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US Patent
n/an/a 50.2n/an/an/an/an/an/a



Chong Kun Dang Pharmaceutical Corp.

US Patent


Assay Description
As a protein source for cholesteryl ester transfer, plasma from healthy persons was used, and as a cholesteryl ester receptor, LDL from healthy perso...

US Patent US9493430 (2016)


BindingDB Entry DOI: 10.7270/Q2W37V7V
More data for this
Ligand-Target Pair