BDBM254059 US9493430, 689

SMILES: COc1cc(cc(c1)-c1ccc(cc1C)C(O)=O)C1=C(CN2[C@@H](C)[C@H](OC2=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)CC(C)(C)CC1

InChI Key: InChIKey=YQBLQCWIDSMAGG-GEFUHLBYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254059   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM254059 (US9493430, 689) Show SMILES COc1cc(cc(c1)-c1ccc(cc1C)C(O)=O)C1=C(CN2[C@@H](C)[C@H](OC2=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)CC(C)(C)CC1 |r,c:20| Show InChI InChI=1S/C36H35F6NO5/c1-19-10-21(32(44)45)6-7-29(19)22-11-23(15-28(14-22)47-5)30-8-9-34(3,4)17-25(30)18-43-20(2)31(48-33(43)46)24-12-26(35(37,38)39)16-27(13-24)36(40,41)42/h6-7,10-16,20,31H,8-9,17-18H2,1-5H3,(H,44,45)/t20-,31-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24.3	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Pharmaceutical Corp. US Patent					Assay Description As a protein source for cholesteryl ester transfer, plasma from healthy persons was used, and as a cholesteryl ester receptor, LDL from healthy perso...				US Patent US9493430 (2016) BindingDB Entry DOI: 10.7270/Q2W37V7V
					More data for this Ligand-Target Pair