BDBM254109 US9481677, 40

SMILES: Fc1cc(c(F)cc1Oc1ccc(Cl)cc1-n1cnc2cncnc12)S(=O)(=O)Nc1ncns1

InChI Key: InChIKey=JAQPLQSHWAIPEO-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254109   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM254109 (US9481677, 40) Show SMILES Fc1cc(c(F)cc1Oc1ccc(Cl)cc1-n1cnc2cncnc12)S(=O)(=O)Nc1ncns1 Show InChI InChI=1S/C19H10ClF2N7O3S2/c20-10-1-2-15(14(3-10)29-9-26-13-6-23-7-24-18(13)29)32-16-4-12(22)17(5-11(16)21)34(30,31)28-19-25-8-27-33-19/h1-9H,(H,25,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
XENON PHARMACEUTICALS INC. US Patent					Assay Description Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (Nav's), and...				US Patent US9481677 (2016) BindingDB Entry DOI: 10.7270/Q20V8BQT
					More data for this Ligand-Target Pair