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SMILES: Oc1cc(ccc1Oc1ccc(cc1Cl)C#N)-c1ccncc1

InChI Key: InChIKey=XNNKBVIHPSHNHS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25424   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Enoyl-ACP reductase


(Plasmodium falciparum)		BDBM25424
PNG
(3-chloro-4-[2-hydroxy-4-(pyridin-4-yl)phenoxy]benz...)
Show SMILES Oc1cc(ccc1Oc1ccc(cc1Cl)C#N)-c1ccncc1
Show InChI InChI=1S/C18H11ClN2O2/c19-15-9-12(11-20)1-3-17(15)23-18-4-2-14(10-16(18)22)13-5-7-21-8-6-13/h1-10,22H
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
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GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.80E+3n/an/an/an/a7.925



Jacobus Pharmaceutical Company



Assay Description
PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...

J Biol Chem 282: 25436-44 (2007)


Article DOI: 10.1074/jbc.M701813200
BindingDB Entry DOI: 10.7270/Q22V2DFD
More data for this
Ligand-Target Pair