null

SMILES: CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(OCCOCCN)c1

InChI Key: InChIKey=HMTVYCCHJJVVJZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 254778   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 8 (Homo sapiens (Human))	BDBM254778 (US9475775, 45 | US9597333, 45) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(OCCOCCN)c1 |t:9,18| Show InChI InChI=1S/C28H37N5O4/c1-3-11-33(12-4-2)28(35)22-16-20-8-9-21(17-25(20)32-26(30)18-22)27(34)31-23-6-5-7-24(19-23)37-15-14-36-13-10-29/h5-9,16-17,19H,3-4,10-15,18,29H2,1-2H3,(H2,30,32)(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254778 (US9475775, 45 | US9597333, 45) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(OCCOCCN)c1 |t:9,18| Show InChI InChI=1S/C28H37N5O4/c1-3-11-33(12-4-2)28(35)22-16-20-8-9-21(17-25(20)32-26(30)18-22)27(34)31-23-6-5-7-24(19-23)37-15-14-36-13-10-29/h5-9,16-17,19H,3-4,10-15,18,29H2,1-2H3,(H2,30,32)(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9597333 (2017) BindingDB Entry DOI: 10.7270/Q2474CXF
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM254778 (US9475775, 45 | US9597333, 45) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(OCCOCCN)c1 |t:9,18| Show InChI InChI=1S/C28H37N5O4/c1-3-11-33(12-4-2)28(35)22-16-20-8-9-21(17-25(20)32-26(30)18-22)27(34)31-23-6-5-7-24(19-23)37-15-14-36-13-10-29/h5-9,16-17,19H,3-4,10-15,18,29H2,1-2H3,(H2,30,32)(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9597333 (2017) BindingDB Entry DOI: 10.7270/Q2474CXF
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254778 (US9475775, 45 | US9597333, 45) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(OCCOCCN)c1 |t:9,18| Show InChI InChI=1S/C28H37N5O4/c1-3-11-33(12-4-2)28(35)22-16-20-8-9-21(17-25(20)32-26(30)18-22)27(34)31-23-6-5-7-24(19-23)37-15-14-36-13-10-29/h5-9,16-17,19H,3-4,10-15,18,29H2,1-2H3,(H2,30,32)(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair