BDBM255636 US9475815, 21

SMILES: COc1cc(C)cc2cc(sc12)-c1cc(CN2CC(O)C(C2)NCCO)n2ncnc(N)c12

InChI Key: InChIKey=DPWPVAXWAAKYQP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 255636   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GST-Fibroblast growth factor receptor 1 (FGFR-1) (Homo sapiens (Human))	BDBM255636 (US9475815, 21) Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CC(O)C(C2)NCCO)n2ncnc(N)c12 Show InChI InChI=1S/C23H28N6O3S/c1-13-5-14-7-20(33-22(14)19(6-13)32-2)16-8-15(29-21(16)23(24)26-12-27-29)9-28-10-17(18(31)11-28)25-3-4-30/h5-8,12,17-18,25,30-31H,3-4,9-11H2,1-2H3,(H2,24,26,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.2	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLETUAL PROPERTY GMBH US Patent					Assay Description A recombinant tagged FGFR-1 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...				US Patent US9475815 (2016) BindingDB Entry DOI: 10.7270/Q2862FC7
					More data for this Ligand-Target Pair
GST-Fibroblast growth factor receptor 3 (FGFR-3) (Homo sapiens (Human))	BDBM255636 (US9475815, 21) Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CC(O)C(C2)NCCO)n2ncnc(N)c12 Show InChI InChI=1S/C23H28N6O3S/c1-13-5-14-7-20(33-22(14)19(6-13)32-2)16-8-15(29-21(16)23(24)26-12-27-29)9-28-10-17(18(31)11-28)25-3-4-30/h5-8,12,17-18,25,30-31H,3-4,9-11H2,1-2H3,(H2,24,26,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLETUAL PROPERTY GMBH US Patent					Assay Description A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...				US Patent US9475815 (2016) BindingDB Entry DOI: 10.7270/Q2862FC7
					More data for this Ligand-Target Pair