BDBM255656 US9475815, 41

SMILES: CNC1CCN(Cc2cc(-c3cc4cc(C)cc(OC)c4s3)c3c(N)ncnn23)C1

InChI Key: InChIKey=DGBOFPNMIOHGJR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 255656   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GST-Fibroblast growth factor receptor 1 (FGFR-1) (Homo sapiens (Human))	BDBM255656 (US9475815, 41) Show SMILES CNC1CCN(Cc2cc(-c3cc4cc(C)cc(OC)c4s3)c3c(N)ncnn23)C1 Show InChI InChI=1S/C22H26N6OS/c1-13-6-14-8-19(30-21(14)18(7-13)29-3)17-9-16(11-27-5-4-15(10-27)24-2)28-20(17)22(23)25-12-26-28/h6-9,12,15,24H,4-5,10-11H2,1-3H3,(H2,23,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.30	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLETUAL PROPERTY GMBH US Patent					Assay Description A recombinant tagged FGFR-1 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...				US Patent US9475815 (2016) BindingDB Entry DOI: 10.7270/Q2862FC7
					More data for this Ligand-Target Pair