BDBM255671 US9475815, 56

SMILES: COc1cc(C)cc2cc(sc12)-c1cc(CN2CCC[C@H](N)C2)n2ncnc(N)c12

InChI Key: InChIKey=RHCJHFBKBLNXCH-HNNXBMFYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 255671   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GST-Fibroblast growth factor receptor 1 (FGFR-1) (Homo sapiens (Human))	BDBM255671 (US9475815, 56) Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CCC[C@H](N)C2)n2ncnc(N)c12 |r| Show InChI InChI=1S/C22H26N6OS/c1-13-6-14-8-19(30-21(14)18(7-13)29-2)17-9-16(11-27-5-3-4-15(23)10-27)28-20(17)22(24)25-12-26-28/h6-9,12,15H,3-5,10-11,23H2,1-2H3,(H2,24,25,26)/t15-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.5	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLETUAL PROPERTY GMBH US Patent					Assay Description A recombinant tagged FGFR-1 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...				US Patent US9475815 (2016) BindingDB Entry DOI: 10.7270/Q2862FC7
					More data for this Ligand-Target Pair
GST-Fibroblast growth factor receptor 3 (FGFR-3) (Homo sapiens (Human))	BDBM255671 (US9475815, 56) Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CCC[C@H](N)C2)n2ncnc(N)c12 |r| Show InChI InChI=1S/C22H26N6OS/c1-13-6-14-8-19(30-21(14)18(7-13)29-2)17-9-16(11-27-5-3-4-15(23)10-27)28-20(17)22(24)25-12-26-28/h6-9,12,15H,3-5,10-11,23H2,1-2H3,(H2,24,25,26)/t15-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22.6	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLETUAL PROPERTY GMBH US Patent					Assay Description A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...				US Patent US9475815 (2016) BindingDB Entry DOI: 10.7270/Q2862FC7
					More data for this Ligand-Target Pair