BDBM255706 US9475815, 91

SMILES: COc1cc(C)cc2cc(sc12)-c1cc(CN2CC(O)C2)n2ncnc(N)c12

InChI Key: InChIKey=PZBQTXOVSDEILA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 255706   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GST-Fibroblast growth factor receptor 1 (FGFR-1) (Homo sapiens (Human))	BDBM255706 (US9475815, 91) Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CC(O)C2)n2ncnc(N)c12 Show InChI InChI=1S/C20H21N5O2S/c1-11-3-12-5-17(28-19(12)16(4-11)27-2)15-6-13(7-24-8-14(26)9-24)25-18(15)20(21)22-10-23-25/h3-6,10,14,26H,7-9H2,1-2H3,(H2,21,22,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36.9	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLETUAL PROPERTY GMBH US Patent					Assay Description A recombinant tagged FGFR-1 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...				US Patent US9475815 (2016) BindingDB Entry DOI: 10.7270/Q2862FC7
					More data for this Ligand-Target Pair
GST-Fibroblast growth factor receptor 3 (FGFR-3) (Homo sapiens (Human))	BDBM255706 (US9475815, 91) Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CC(O)C2)n2ncnc(N)c12 Show InChI InChI=1S/C20H21N5O2S/c1-11-3-12-5-17(28-19(12)16(4-11)27-2)15-6-13(7-24-8-14(26)9-24)25-18(15)20(21)22-10-23-25/h3-6,10,14,26H,7-9H2,1-2H3,(H2,21,22,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23.9	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLETUAL PROPERTY GMBH US Patent					Assay Description A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...				US Patent US9475815 (2016) BindingDB Entry DOI: 10.7270/Q2862FC7
					More data for this Ligand-Target Pair