BDBM255713 US9475815, 98

SMILES: COc1cc(C)cc2cc(sc12)-c1cc(C(=O)NC2CCNC2=O)n2ncnc(N)c12

InChI Key: InChIKey=UTIDFSKVEIKIKB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 255713   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GST-Fibroblast growth factor receptor 1 (FGFR-1) (Homo sapiens (Human))	BDBM255713 (US9475815, 98) Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(C(=O)NC2CCNC2=O)n2ncnc(N)c12 Show InChI InChI=1S/C21H20N6O3S/c1-10-5-11-7-16(31-18(11)15(6-10)30-2)12-8-14(27-17(12)19(22)24-9-25-27)21(29)26-13-3-4-23-20(13)28/h5-9,13H,3-4H2,1-2H3,(H,23,28)(H,26,29)(H2,22,24,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLETUAL PROPERTY GMBH US Patent					Assay Description A recombinant tagged FGFR-1 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...				US Patent US9475815 (2016) BindingDB Entry DOI: 10.7270/Q2862FC7
					More data for this Ligand-Target Pair
GST-Fibroblast growth factor receptor 3 (FGFR-3) (Homo sapiens (Human))	BDBM255713 (US9475815, 98) Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(C(=O)NC2CCNC2=O)n2ncnc(N)c12 Show InChI InChI=1S/C21H20N6O3S/c1-10-5-11-7-16(31-18(11)15(6-10)30-2)12-8-14(27-17(12)19(22)24-9-25-27)21(29)26-13-3-4-23-20(13)28/h5-9,13H,3-4H2,1-2H3,(H,23,28)(H,26,29)(H2,22,24,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.1	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLETUAL PROPERTY GMBH US Patent					Assay Description A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...				US Patent US9475815 (2016) BindingDB Entry DOI: 10.7270/Q2862FC7
					More data for this Ligand-Target Pair